Kick-off is at 8pm UK time on BBC Two and BBC iPlayer. Chelsea face injury absences for Bjorn, Ramirez, and Bright, while Arsenal are without Cooney-Cross, Zinsberger, and Reid.
Arsenal are unbeaten since January, while Chelsea look for a comeback. Managers Sonia Bompastor and Renee Slegers both expressed confidence ahead of the crucial second leg.